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Definition:
A malignancy in the liver that is not HCC. Examples include intrahepatic cholangiocarcinoma (ICC), metastasis, lymphoma, and post-transplant lymphoproliferative disorder.
LI-RADS Categorization:
- Observations thought to represent a non-HCC malignancy should be categorized LR-M.
Characteristic imaging features:
- Features that favor non-HCC malignancy over HCC include (partial list):
- Features that favor HCC over non-HCC malignancy include (partial list):
Background:
- HCC is the most common malignancy in patients with cirrhosis or other risk factors for HCC. Non-HCC malignancies may occur, however. Differentiation between HCC and non-HCC malignancy is important as the management and prognosis differ.
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