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Blood products

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Definition:

Presence of intra-lesional or peri-lesional hemorrhage in absence of biopsy, trauma or intervention.

Usage:

  • Blood products in or around a lesion in the absence of biopsy, trauma, or intervention is an ancillary feature favoring malignancy.
  • Radiologists at their discretion may apply this ancillary feature to upgrade category (up to LR-4).
  • MRI is more sensitive and specific for detection of blood products than CT.
  • At MRI, blood products usually manifest as areas of heterogeneous, predominantly high signal intensity on T1w images and heterogeneous, predominantly low signal intensity on T2w images. Due to T2* shortening, there may be signal loss on the second echo of a dual-echo gradient-echo sequence.
  • At CT, blood products usually manifest as areas of heterogeneous hyperattenuation. 
If unsure about feature:
  • Do not characterize as blood products
Synonyms:
  • Hematoma, hemorrhage

Potential pitfalls and challenges:

  • Diameter reduction should not be used as an ancillary feature favoring benignity in observations that reduce in size following resorption of acute bleed.



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