Definition:
Usage
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Applies to observations that unequivocally:
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Are homogeneously and markedly hypointense relative to liver on T2w or T2*w images or that have moderate or marked signal loss on the second echo of a dual-echo imaging acquisition. The hypointensity relative to liver is more pronounced with longer echo times and, if dual-echo imaging is performed, with greater echo spacing. Note that fat will also result in signal loss on second echo of dual-echo imaging if out-of-phase echo is acquired after the in-phase echo and distinction between T2* effects and fat can be difficult in this situation.
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Also applies to masses that are a conglomeration of smaller nodules, each of which is uniform in size and appearance including homogeneous and marked hypointensity relative to liver on T2w or T2*w images. This differs from multi-nodule-in-nodule appearance in which the individual nodules differ in size or appearance.
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Homogeneous marked T2 or T2* hypointensity is an ancillary feature favoring benignity.
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Radiologists at their discretion may apply homogeneous marked T2 or T2* hypointensity to downgrade category.
If unsure about feature:
Synonyms:
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Synonyms: T2 Hypointensity, Low T2 Signal
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Preferred terms: Homogeneous marked T2 or T2* hypointensity
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Rationale for preferred terms: Most descriptive term
Background:
References:
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