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Probable benign entities (examples)
Comment:
- With few exceptions, the list of definite benign entities and probable benign entities is the same. The categorization as LR-1 or LR-2 depends on the level of certainty.
- Observations with features diagnostic of a benign entity are categorized LR-1.
- Observations with features suggestive of but not diagnostic of a benign entity are categorized LR-2. For example, an observation thought to be a benign entity but with atypical imaging features is appropriately categorized LR-2.
- Observations with features equivocal for benign entities, that do not meet LR-4 or LR-5 criteria and that do not have features suggestive of non-HCC malignancy should be categorized LR-3.
- LI-RADS v2014 purposely does not list focal nodular hyperplasia (FNH) or hepatocellular adenoma (HCA) as examples of benign entities.
- Rationale: Although FNH-like lesions may occur in cirrhosis, they are rare and they are difficult to diagnose reliably by non-invasive imaging. HCAs are rare in cirrhosis.
- LI-RADS v2014 does not address regenerative nodules occurring in the absence of cirrhosis (e.g., Budd-Chiari-associated RNs)
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